Bioactive Isocoumarins and Related Metabolites from Conifer Endophytes

Six new [1-4, 7, 9] and two known [6 and 8] metabolites have been isolated from culture filtrates of conifer endophyte strains of Canoplea elegantula. Their structures have been determined by spectroscopic means. Compound 1 was toxic to spruce budworm cells, and both 1 and 3 were toxic to spruce bud...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1995-11, Vol.58 (11), p.1759-1766
Hauptverfasser:	Findlay, John A, Buthelezi, Sentsetsa, Lavoie, Rico, Peña-Rodriguez, Luis, Miller, J. David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological control Canada Choristoneura fumiferana Control Coumarins - chemistry Coumarins - isolation & purification Coumarins - toxicity Fundamental and applied biological sciences. Psychology Insecticides - chemistry Insecticides - isolation & purification Insecticides - toxicity Larva Lepidoptera Phytopathology. Animal pests. Plant and forest protection Plants, Toxic - chemistry Protozoa. Invertebrates Tortricidae
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Beschreibung
Zusammenfassung:	Six new [1-4, 7, 9] and two known [6 and 8] metabolites have been isolated from culture filtrates of conifer endophyte strains of Canoplea elegantula. Their structures have been determined by spectroscopic means. Compound 1 was toxic to spruce budworm cells, and both 1 and 3 were toxic to spruce budworm larvae.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np50125a021