ACQUIRED DRUG RESISTANCE DURING INADEQUATE THERAPY IN A YOUNG CHILD WITH TUBERCULOSIS

Drug resistance in children with tuberculosis is usually primary (transmitted); however, resistance acquisition during treatment is possible. We describe a child with tuberculosis who acquired drug resistance while receiving directly observed but inadequate first-line therapy and the programmatic an...

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Veröffentlicht in:The Pediatric infectious disease journal 2014-08, Vol.33 (8), p.883-885
Hauptverfasser: GARCIA-PRATS, Anthony J, WILLEMSE, Marianne, SEIFART, Heiner I, JORDAAN, Annemie M, WERELY, Cedric J, DONALD, Peter R, SCHAAF, H. Simon
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container_end_page 885
container_issue 8
container_start_page 883
container_title The Pediatric infectious disease journal
container_volume 33
creator GARCIA-PRATS, Anthony J
WILLEMSE, Marianne
SEIFART, Heiner I
JORDAAN, Annemie M
WERELY, Cedric J
DONALD, Peter R
SCHAAF, H. Simon
description Drug resistance in children with tuberculosis is usually primary (transmitted); however, resistance acquisition during treatment is possible. We describe a child with tuberculosis who acquired drug resistance while receiving directly observed but inadequate first-line therapy and the programmatic and clinical factors that may have contributed to resistance acquisition.
doi_str_mv 10.1097/INF.0000000000000336
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subjects Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antitubercular Agents - administration & dosage
Antitubercular Agents - pharmacology
Bacterial diseases
Biological and medical sciences
Child, Preschool
Drug Resistance, Multiple, Bacterial
Human bacterial diseases
Humans
Infectious diseases
Male
Medical sciences
Mycobacterium tuberculosis - drug effects
Pharmacology. Drug treatments
Tuberculosis and atypical mycobacterial infections
Tuberculosis, Multidrug-Resistant - drug therapy
Tuberculosis, Multidrug-Resistant - microbiology
Tuberculosis, Pulmonary - drug therapy
Tuberculosis, Pulmonary - microbiology
title ACQUIRED DRUG RESISTANCE DURING INADEQUATE THERAPY IN A YOUNG CHILD WITH TUBERCULOSIS
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