Risk prediction of complications of metabolic syndrome before and 6 years after gastric bypass

Abstract Background Roux-en-Y gastric bypass (RYGB) surgery has been shown to have favorable effects on components of metabolic syndrome. However, the long-term effect of RYGB on predicted risk of end-organ complications is less clear. The objective of this study was to examine long-term changes in predicted risk of metabolic syndrome-related complications after RYGB. Methods The predicted risk of metabolic syndrome-related complications in a cohort of 131 diabetic patients was compared between baseline and last follow-up points after RYGB using validated risk assessment tools. Results After a median postsurgical follow-up time of 6 years (range, 5–9), a mean percent excess weight loss of 60.7±25.1% was associated with a diabetes remission rate of 61%. At long-term follow-up, the levels of glycated hemoglobin, low-density lipoprotein, and blood pressure were within the recommended American Diabetes Association’s goals in 85%, 73%, and 63% of patients, respectively ( P