Outcomes in Patients With Various Forms of Aortic Stenosis Including Those With Low-Flow Low-Gradient Normal and Low Ejection Fraction

Low-flow low-gradient aortic stenosis with normal ejection fraction (LFLGNEF AS) is a newly characterized poorly understood entity within the AS spectrum. Whether LFLGNEF AS has a worse prognosis than typical AS remains controversial. We retrospectively identified 4,546 individual patients with any...

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Veröffentlicht in:	The American journal of cardiology 2014-10, Vol.114 (7), p.1069-1074
Hauptverfasser:	Romero, Jorge, MD, Chavez, Patricia, MD, Goodman-Meza, David, MD, MS, Holmes, Anthony A., MD, Ostfeld, Robert J., MD, MS, Manheimer, Eric D., MD, Siegel, Robert M., MD, Lupercio, Florentino, MD, Shulman, Eric H., MD, Liakos, Matthew, MD, Garcia, Mario J., MD, MS, Spevack, Daniel M., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Aortic Valve Stenosis - mortality Aortic Valve Stenosis - physiopathology Aortic Valve Stenosis - surgery Cardiology Cardiovascular Coronary vessels Echocardiography, Doppler Female Follow-Up Studies Heart attacks Heart Valve Prosthesis Implantation Heart Ventricles - diagnostic imaging Heart Ventricles - physiopathology Humans Male Mortality New York - epidemiology Prognosis Retrospective Studies Severity of Illness Index Stroke Volume Survival Rate - trends Ventricular Function, Left - physiology
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Zusammenfassung:	Low-flow low-gradient aortic stenosis with normal ejection fraction (LFLGNEF AS) is a newly characterized poorly understood entity within the AS spectrum. Whether LFLGNEF AS has a worse prognosis than typical AS remains controversial. We retrospectively identified 4,546 individual patients with any type of AS on echocardiogram from 2003 through 2013 and categorized them into 5 cohorts: (1) mild AS, (2) moderate AS, (3) severe AS, (4) LFLGNEF AS (ejection fraction ≥55%), and (5) low-flow low-gradient low ejection fraction AS (LFLGLEF AS; ejection fraction
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2014.07.020