Density-dependent nerve growth factor regulation of G sub(s)- alpha RNA in pheochromocytoma 12 cells
Nerve growth factor (NGF) affects levels of the alpha subunit of the stimulatory G protein (G sub(s)- alpha ) in pheochromocytoma 12 cells in a bidirectional, density-dependent manner. Cells grown at high density responded to NGF treatment with increased levels of G sub(2)- alpha mRNA and protein. C...
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Veröffentlicht in: | Molecular and cellular biology 1990-01, Vol.10 (6), p.3277-3279 |
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creator | Tjaden, G Aguanno, A Kumar, R Benincasa, D Gubits, R M Yu, Hong Dolan, K P |
description | Nerve growth factor (NGF) affects levels of the alpha subunit of the stimulatory G protein (G sub(s)- alpha ) in pheochromocytoma 12 cells in a bidirectional, density-dependent manner. Cells grown at high density responded to NGF treatment with increased levels of G sub(2)- alpha mRNA and protein. Conversely, in cells growth in low-density cultures, levels of this mRNA were lowered by NGF treatment. |
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title | Density-dependent nerve growth factor regulation of G sub(s)- alpha RNA in pheochromocytoma 12 cells |
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