Density-dependent nerve growth factor regulation of G sub(s)- alpha RNA in pheochromocytoma 12 cells

Density-dependent nerve growth factor regulation of G sub(s)- alpha RNA in pheochromocytoma 12 cells

Nerve growth factor (NGF) affects levels of the alpha subunit of the stimulatory G protein (G sub(s)- alpha ) in pheochromocytoma 12 cells in a bidirectional, density-dependent manner. Cells grown at high density responded to NGF treatment with increased levels of G sub(2)- alpha mRNA and protein. C...

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Veröffentlicht in:Molecular and cellular biology 1990-01, Vol.10 (6), p.3277-3279
Hauptverfasser: Tjaden, G, Aguanno, A, Kumar, R, Benincasa, D, Gubits, R M, Yu, Hong, Dolan, K P
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Sprache:eng
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Zusammenfassung:Nerve growth factor (NGF) affects levels of the alpha subunit of the stimulatory G protein (G sub(s)- alpha ) in pheochromocytoma 12 cells in a bidirectional, density-dependent manner. Cells grown at high density responded to NGF treatment with increased levels of G sub(2)- alpha mRNA and protein. Conversely, in cells growth in low-density cultures, levels of this mRNA were lowered by NGF treatment.
ISSN:0270-7306