Structure analysis of modified oligodeoxyribonucleotides by negative ion fast atom bombardment mass spectrometry

Negative ion fast atom bombardment mass spectrometry is used to verify the sequence of oligodeoxyribonucleotides containing a single modified nucleotide. Both the position in the sequence and the molecular weight of the modified nucleotide can be determined from the 3′ and 5′‐phosphate sequence ions...

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Veröffentlicht in:	Biological Mass Spectrometry 1989-08, Vol.18 (8), p.617-619
Hauptverfasser:	Iden, Charles R., Rieger, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology Nucleic acids Nucleic bases, nucleotides
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Negative ion fast atom bombardment mass spectrometry is used to verify the sequence of oligodeoxyribonucleotides containing a single modified nucleotide. Both the position in the sequence and the molecular weight of the modified nucleotide can be determined from the 3′ and 5′‐phosphate sequence ions which are prominent in the mass spectrum.
ISSN:	0887-6134 1096-9888 2376-3868
DOI:	10.1002/bms.1200180818