Effect of zusanli (ST 36) moxibustion on rat mesenteric microvascular system

To investigate the effect of moxibustion on Zusanli (ST 36) on visceral-mesenteric vessels by observing circulation. Forty-five SD rats were randomly assigned to a moxibustion, electroacupuncture (EA), and blank group. In the moxibustion group, heat stimulation of moxibustion to the Zusanli (ST 36) area of normal rats was performed for 15 min. In the EA group, needles were inserted into the Zusanli (ST 36) and lateral point [0.5 cm lateral from Zusanli (ST 36)] for 15 min. The blank group was not given any treatment. We continuously monitored mesenteric microvascular changes with in vivo microscopic video. Moxibustion and EA to Zusanli (ST 36) increase the diameter of mesenteric arterioles and venules (P < 0.05). There were no obvious changes in the blank group. Fine arterial diameter peaked at 12 min in the moxibustion group, while it peaked at 15 min in the EA group. The stimulation of moxibustion and acupuncture to Zusanli (ST 36) has immediate effects on expanding the microvasculature. This dilation may be the mechanism of the gastrointestinal effect of Zusanli (ST 36).