Capacity of multidrug-resistant clinical isolates of Acinetobacter baumannii to form biofilm and adhere to epithelial cell surfaces

This study evaluated the capacity of 23 multidrug-resistant (MDR) clinical isolates of Acinetobacter baumannii to adhere to respiratory epithelial cell surfaces and to form biofilm on a polystyrene surface. All 23 A. baumannii isolates were capable of adhering efficiently to respiratory epithelial c...

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Veröffentlicht in:	Clinical microbiology and infection 2008-01, Vol.14 (1), p.49-54
Hauptverfasser:	Lee, H.-W., Koh, Y.M., Kim, J., Lee, J.-C., Lee, Y.-C., Seol, S.-Y., Cho, D.-T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Acinetobacter baumannii - drug effects Acinetobacter baumannii - genetics Acinetobacter baumannii - physiology Acinetobacter Infections - microbiology adherence Anti-Bacterial Agents - pharmacology Bacterial Adhesion - physiology Bacteriology beta-Lactamases - genetics biofilm formation on epithelial cells Biofilms - drug effects Biofilms - growth & development Biological and medical sciences Cell Line Drug Resistance, Multiple, Bacterial Edetic Acid - pharmacology Epithelial Cells - microbiology Fundamental and applied biological sciences. Psychology Humans Microbiology multidrug resistance Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains PER-1 β-lactamase Respiratory Mucosa - microbiology
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Zusammenfassung:	This study evaluated the capacity of 23 multidrug-resistant (MDR) clinical isolates of Acinetobacter baumannii to adhere to respiratory epithelial cell surfaces and to form biofilm on a polystyrene surface. All 23 A. baumannii isolates were capable of adhering efficiently to respiratory epithelial cells, and biofilm production was positively associated with epithelial cell adhesiveness (r 0.80, p
ISSN:	1198-743X 1469-0691
DOI:	10.1111/j.1469-0691.2007.01842.x