Antibiotic Resistance Issues in Clinical Pathogens: A Review

Antibiotic resistance in pathogens is on the increase but in the past few decades this problem raised a deepening concern among scientific community in terms of the clinical management of infectious diseases. In this review, the common gram negative clinically significant pathogenic bacteria who have acquired resistance with passage of time like Shigella dysenteriae, Sh. Boydii, Sh. Flexneri, Listeria monocytogenes, Acinetobacter baumannii, acinetobacter, A. baumannii, Morganella morganii, Enterobacteriaceae, Citrobacter freundii, Citrobacter braakii, or Citrobacter amalonaticus, P. stuartii, Providencia rettgeri, P. alcalifaciens, P. rustigianii, E. coli, Salmonella. paratyphi, S. typhi, Salmonella enterica, have been compiled with their plausible ways of causing resistance. We conclude from our literature review that resistance in gram negative bacteria is on the rise and new and advanced antibiotics need to be designed and introduced.