Full remission of tardive dyskinesia following general anaesthesia

A 44 year old woman with a severe drug induced tardive dyskinesia had previously been treated with a left thalamotomy and right deep brain stimulation. Thalamotomy abolished the right hemiballismus. Deep brain stimulation caused a moderate reduction of the remaining involuntary movements on the left...

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Veröffentlicht in:	Journal of neurology 2002-05, Vol.249 (5), p.622-625
Hauptverfasser:	JOHNSEN, Mads, WESTER, Knut
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Androstanols - therapeutic use Anesthetics, General - therapeutic use Antipsychotic Agents - adverse effects Biological and medical sciences Brain - drug effects Brain - physiopathology Brain - surgery Dyskinesia, Drug-Induced - drug therapy Dyskinesia, Drug-Induced - etiology Dyskinesia, Drug-Induced - physiopathology Female Femoral Neck Fractures - surgery Fentanyl - therapeutic use Flupenthixol - adverse effects Humans Isoflurane - therapeutic use Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neurosurgical Procedures Receptors, Dopamine - drug effects Receptors, Dopamine - metabolism Remission Induction - methods Thalamus - surgery Thiopental - therapeutic use
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Beschreibung
Zusammenfassung:	A 44 year old woman with a severe drug induced tardive dyskinesia had previously been treated with a left thalamotomy and right deep brain stimulation. Thalamotomy abolished the right hemiballismus. Deep brain stimulation caused a moderate reduction of the remaining involuntary movements on the left side. After a minor orthopaedic operation under general anaesthesia, the dyskinesia disappeared completely, even with the deep brain stimulation turned off. The remission has now lasted for 41 months.
ISSN:	0340-5354 1432-1459
DOI:	10.1007/s004150200073