Effects of Different Antigenic Stimuli on Thymic Function and Interleukin-7/CD127 System in Patients with Chronic HIV Infection

BACKGROUND:We tested if an increase in immune activation and a decrease in CD4 T cells induced by different antigenic stimuli could be associated with changes in the thymic function and the interleukin (IL)-7/CD127 system. METHODS:Twenty-six HIV-infected patients under combined antiretroviral therap...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2014-08, Vol.66 (5), p.466-472
Hauptverfasser:	Castro, Pedro, Torres, Berta, López, Anna, González, Raquel, Vilella, Anna, Nicolas, Jose M, Gallart, Teresa, Pumarola, Tomàs, Sánchez, Marcelo, Leal, Manuel, Vallejo, Alejandro, Bayas, José M, Gatell, José M, Plana, Montserrat, García, Felipe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS Vaccines AIDS/HIV Anti-HIV Agents Antigens Antiretroviral drugs CD4 Lymphocyte Count Chronic Disease Cohort Studies Cytokines Double-Blind Method Female Gene Expression Regulation - immunology HIV HIV Infections - immunology HIV Infections - metabolism Human immunodeficiency virus Humans Interleukin-7 - genetics Interleukin-7 - metabolism Male Middle Aged Receptors, Interleukin-7 - genetics Receptors, Interleukin-7 - metabolism Risk Factors T cell receptors Thymus Gland - physiology Vaccines Viral Load Viremia
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