Design and synthesis of anthracene-based bispyridinium amides: anion binding, cell staining and DNA interaction studies

The design and synthesis of anthracene labeled bispyridinium amides 1-4 along with their anion binding, cell staining and DNA interaction studies are reported. All the chemosensors exhibit significant response towards H sub(2)PO sub(4) super(-) in CH sub(3)CN. Furthermore, sensors 2 and 3 are quite...

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Veröffentlicht in:New journal of chemistry 2012-01, Vol.36 (5), p.1231-1245
Hauptverfasser: Ghosh, Kumaresh, Sarkar, Avik Ranjan, Ghorai, Atanu, Ghosh, Utpal
Format: Artikel
Sprache:eng
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Zusammenfassung:The design and synthesis of anthracene labeled bispyridinium amides 1-4 along with their anion binding, cell staining and DNA interaction studies are reported. All the chemosensors exhibit significant response towards H sub(2)PO sub(4) super(-) in CH sub(3)CN. Furthermore, sensors 2 and 3 are quite interesting for the selective sensing of aliphatic dicarboxylates. Among these compounds, 1 is found to be useful in cell staining. Also all of them exhibit significant interaction with DNA. All these properties are found to be dependent on the nature of the spacer that holds the pyridinium binding sites.
ISSN:1144-0546
1369-9261
DOI:10.1039/c2nj21024j