Simultaneous SERS detection and imaging of two biomarkers on the cancer cell surface by self-assembly of branched DNA-gold nanoaggregates

A surface-enhanced Raman scattering (SERS) method has been proposed for simultaneous detection and imaging of two biomarkers on the surface of a single human breast cancer cell (MCF-7) by self-assembly of branched DNA-gold nanoaggregates.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2014-09, Vol.50 (69), p.9907-9909
Hauptverfasser:	Li, Ying, Qi, Xindi, Lei, Chengcun, Yue, Qifeng, Zhang, Shusheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - analysis Breast - pathology Breast Neoplasms - diagnosis Diagnostic Imaging DNA - chemistry Female Gold - chemistry Humans MCF-7 Cells Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure Spectrum Analysis, Raman - methods
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Beschreibung
Zusammenfassung:	A surface-enhanced Raman scattering (SERS) method has been proposed for simultaneous detection and imaging of two biomarkers on the surface of a single human breast cancer cell (MCF-7) by self-assembly of branched DNA-gold nanoaggregates.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c4cc05226a