Metabolically-Healthy Obesity and Coronary Artery Calcification

Objectives The purpose of this study was to compare the coronary artery calcium (CAC) scores of metabolically-healthy obese (MHO) and metabolically healthy normal-weight individuals in a large sample of apparently healthy men and women. Background The risk of cardiovascular disease among obese indiv...

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Veröffentlicht in:	Journal of the American College of Cardiology 2014-06, Vol.63 (24), p.2679-2686
Hauptverfasser:	Chang, Yoosoo, MD, Kim, Bo-Kyoung, MD, Yun, Kyung Eun, MD, PhD, Cho, Juhee, PhD, Zhang, Yiyi, PhD, Rampal, Sanjay, MD, Zhao, Di, MHS, Jung, Hyun-Suk, MD, Choi, Yuni, BS, Ahn, Jiin, MSPH, Lima, João A.C., MD, Shin, Hocheol, MD, PhD, Guallar, Eliseo, MD, DrPH, Ryu, Seungho, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Alcohol use Biological and medical sciences Blood pressure Body mass index Cardiology Cardiology. Vascular system Cardiovascular cardiovascular disease Cholesterol College graduates Confidence intervals coronary artery calcium score coronary artery disease Coronary Artery Disease - diagnosis Coronary Artery Disease - epidemiology Coronary Artery Disease - metabolism Cross-Sectional Studies Education Exercise Female Glucose Health Status Heart Homeostasis Hospitals Humans Hypertension Insulin Insulin resistance Internal Medicine Lipoproteins Male Medical sciences Mens health Metabolic diseases metabolically-healthy obesity Middle Aged Obesity Obesity - diagnosis Obesity - epidemiology Obesity - metabolism Physical fitness Republic of Korea - epidemiology Triglycerides Values Vascular Calcification - diagnosis Vascular Calcification - epidemiology Vascular Calcification - metabolism Women
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Zusammenfassung:	Objectives The purpose of this study was to compare the coronary artery calcium (CAC) scores of metabolically-healthy obese (MHO) and metabolically healthy normal-weight individuals in a large sample of apparently healthy men and women. Background The risk of cardiovascular disease among obese individuals without obesity-related metabolic abnormalities, referred to as MHO, is controversial. Methods We conducted a cross-sectional study of 14,828 metabolically-healthy adults with no known cardiovascular disease who underwent a health checkup examination that included estimation of CAC scores by cardiac tomography. Being metabolically healthy was defined as not having any metabolic syndrome component and having a homeostasis model assessment of insulin resistance
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2014.03.042