Synthesis and Antimicrobial activity of 3-Arylhydrazono-2,4-Dioxoalkanoate Esters

A simple and convenient method for the synthesis of 3-arylhydrazono-2,4-dioxoalkanoate esters was proposed. The structures of the synthesized compounds were established based on PMR and IR spectroscopic data and an x-ray crystal structure analysis. The antimicrobial activity of these compounds was i...

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Veröffentlicht in:Pharmaceutical chemistry journal 2014, Vol.47 (10), p.531-535
Hauptverfasser: Levenets, T. V., Kozminykh, V. O.
Format: Artikel
Sprache:eng
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Zusammenfassung:A simple and convenient method for the synthesis of 3-arylhydrazono-2,4-dioxoalkanoate esters was proposed. The structures of the synthesized compounds were established based on PMR and IR spectroscopic data and an x-ray crystal structure analysis. The antimicrobial activity of these compounds was investigated. It was found that some of the tested compounds exhibited pronounced antimicrobial effects with respect to Staphylococcus aureus P-209 strains.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-014-0998-6