Anti-inflammatory and anti-pyretic properties of Spirulina platensis and Spirulina lonar: a comparative study

Spirulina spp. is a blue-green algae belongs to the family of Oscillatoriaceae, which having diverse biological activity. The aim of this current study was to evaluate and compare the anti-pyretic and anti-inflammatory activity of Spirulina platensis/SP and Spirulina lonar/SL extracts. In the anti-p...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2014-09, Vol.27 (5), p.1277-1280
Hauptverfasser:	Somchit, Muhammad Nazrul, Mohamed, Nor Azura, Ahmad, Zuraini, Zakaria, Zainul Amiruddin, Shamsuddin, Lokman, Omar-Fauzee, Mohd Sofian, Kadir, Arifah Abdul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Antipyretics - pharmacology Body Temperature - drug effects Care and treatment Comparative analysis Dose-Response Relationship, Drug Fever Health aspects Hyperthermia Inflammation Medicinal plants Plant Extracts - pharmacology Rats Spirulina
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Zusammenfassung:	Spirulina spp. is a blue-green algae belongs to the family of Oscillatoriaceae, which having diverse biological activity. The aim of this current study was to evaluate and compare the anti-pyretic and anti-inflammatory activity of Spirulina platensis/SP and Spirulina lonar/SL extracts. In the anti-pyretic study, the ability to reduce the rectal temperature of rats induced pyrexia with 2g/kg Brewer's Yeast (BY) was performed. Rats were dosed either 2 or 4 mg/kg SP or SL. Rectal temperature was taken every hour for 8 hours. Results shown that there were significant dose-dependent (p
ISSN:	1011-601X