Peripheral neuropathy in primary HIV infection associates with systemic and central nervous system immune activation

Peripheral neuropathy (PN) is a frequent complication of chronic HIV infection. We prospectively studied individuals with primary HIV infection (

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2014-07, Vol.66 (3), p.303-310
Hauptverfasser:	Wang, Samantha X Y, Ho, Emily L, Grill, Marie, Lee, Evelyn, Peterson, Julia, Robertson, Kevin, Fuchs, Dietmar, Sinclair, Elizabeth, Price, Richard W, Spudich, Serena
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Antiretroviral drugs Biomarkers - blood Biomarkers - cerebrospinal fluid CD4 Lymphocyte Count CD8-Positive T-Lymphocytes - cytology Chemokine CCL2 - blood Chemokine CCL2 - cerebrospinal fluid Chemokine CXCL10 - blood Chemokine CXCL10 - cerebrospinal fluid Chronic Disease Cross-Sectional Studies Disease transmission HIV HIV Infections - blood HIV Infections - cerebrospinal fluid HIV Infections - complications HIV Infections - immunology Human immunodeficiency virus Humans Leukocyte Count Male Middle Aged Neopterin - blood Neopterin - cerebrospinal fluid Nervous system Peripheral Nervous System Diseases - immunology Peripheral Nervous System Diseases - virology Prospective Studies Proteins Regression Analysis Ribonucleic acid RNA RNA, Viral - blood RNA, Viral - cerebrospinal fluid
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Beschreibung
Zusammenfassung:	Peripheral neuropathy (PN) is a frequent complication of chronic HIV infection. We prospectively studied individuals with primary HIV infection (
ISSN:	1525-4135 1944-7884
DOI:	10.1097/QAI.0000000000000167