Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in New-Onset Type 1 Diabetes: A Multicenter Analysis

Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in New-Onset Type 1 Diabetes: A Multicenter Analysis

Type 1 diabetes (T1D) is one of the major autoimmune diseases affecting children and young adults worldwide. To date, the different immunotherapies tested have achieved insulin independence in

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Bibliographische Detailangaben
Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2014-09, Vol.63 (9), p.3041-3046
Hauptverfasser: D'ADDIO, Francesca, VASQUEZ, Alessandro Valderrama, BEN NASR, Moufida, FRANEK, Edward, DALONG ZHU, LIRONG LI, GUANG NING, SNARSKI, Emilian, FIORINA, Paolo
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Autoimmune diseases
Biological and medical sciences
C-Peptide - metabolism
Child
Children & youth
Cyclophosphamide - therapeutic use
Diabetes Mellitus, Type 1 - therapy
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Hematopoietic Stem Cell Transplantation - adverse effects
Humans
Immune system
Immunosuppression
Immunotherapy
Insulin - therapeutic use
Male
Medical sciences
Peptides
Remission Induction
Stem cells
Transplantation, Autologous
Transplants & implants
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Beschreibung
Zusammenfassung:Type 1 diabetes (T1D) is one of the major autoimmune diseases affecting children and young adults worldwide. To date, the different immunotherapies tested have achieved insulin independence in
ISSN:0012-1797
1939-327X
DOI:10.2337/db14-0295