A central nervous system B-cell lymphoma arising two years after initial diagnosis of CLIPPERS

Highlights • CLIPPERS is a relapsing-remitting brainstem disease of unknown origin • Sentinel lesions of primary CNS lymphoma could fit all features of CLIPPERS • Including our patient, three cases of CLIPPERS progressed to CNS B-cell lymphoma • CLIPPERS and CNS lymphoma are two distinct diseases or...

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Veröffentlicht in:	Journal of the neurological sciences 2014-09, Vol.344 (1), p.224-226
Hauptverfasser:	Taieb, Guillaume, Uro-Coste, Emmanuelle, Clanet, Michel, Lassmann, Hans, Benouaich-Amiel, Alexandra, Laurent, Camille, Delisle, Marie-Bernadette, Labauge, Pierre, Brassat, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - metabolism Autoimmune disorder Central Nervous System Diseases - complications Chronic Disease Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids Disease Progression Humans Inflammation - complications Lymphoma, B-Cell - etiology Magnetic Resonance Imaging Male Middle Aged Neurology Pathophysiology Pons - pathology Primary CNS lymphoma Primary CNS lymphomatoid granulomatosis Sentinel lesions
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Beschreibung
Zusammenfassung:	Highlights • CLIPPERS is a relapsing-remitting brainstem disease of unknown origin • Sentinel lesions of primary CNS lymphoma could fit all features of CLIPPERS • Including our patient, three cases of CLIPPERS progressed to CNS B-cell lymphoma • CLIPPERS and CNS lymphoma are two distinct diseases or belong to the same disorder? • Further investigations are needed to determine the pathophysiology of CLIPPERS
ISSN:	0022-510X 1878-5883
DOI:	10.1016/j.jns.2014.06.015