Recombinant allergens rarely allow identification of Hymenoptera venom–allergic patients with negative specific IgE to whole venom preparations

Recombinant allergens rarely allow identification of Hymenoptera venom–allergic patients with negative specific IgE to whole venom preparations

[...]while recombinant Hymenoptera venom allergens play an important role in the differentiation between genuine sensitization to and cross-reactivity between honeybee and vespid venoms,5-7 they provide no significant improvement over current venom extract tests in their ability to detect Hymenopter...

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Veröffentlicht in:Journal of allergy and clinical immunology 2014-08, Vol.134 (2), p.493-494.e1
Hauptverfasser: Rafei-Shamsabadi, David, MD, Müller, Sabine, MD, Pfützner, Wolfgang, MD, Spillner, Edzard, PhD, Ruëff, Franziska, MD, Jakob, Thilo, MD
Format: Artikel
Sprache:eng
Schlagworte:
Allergens - immunology
Allergies
Allergy and Immunology
Animals
Arthropod Venoms - immunology
Bees
Humans
Hymenoptera - immunology
Patients
Venom
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Beschreibung
Zusammenfassung:[...]while recombinant Hymenoptera venom allergens play an important role in the differentiation between genuine sensitization to and cross-reactivity between honeybee and vespid venoms,5-7 they provide no significant improvement over current venom extract tests in their ability to detect Hymenoptera venom-allergic patients.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.05.035