The screening of the 3'UTR sequence of LRRK2 identified an association between the rs66737902 polymorphism and Parkinson's disease

Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are the most common genetic determinants of familial and sporadic Parkinson's disease (PD). Most of the mutational screenings analyzed the exon-coding sequence. Our aim was to determine whether LRRK2 3' untranslated region (UTR) va...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of human genetics 2014-06, Vol.59 (6), p.346-348
Hauptverfasser:	Cardo, Lucía F, Coto, Eliecer, Ribacoba, René, Mata, Ignacio F, Moris, Germán, Menéndez, Manuel, Alvarez, Victoria
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Case-Control Studies Genetic Association Studies Genetic Predisposition to Disease Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Male MicroRNAs - metabolism Middle Aged Parkinson Disease - genetics Parkinson Disease - metabolism Polymorphism, Single Nucleotide Protein-Serine-Threonine Kinases - genetics Substantia Nigra - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!