Randomised clinical trial: polyethylene glycol 3350 with sports drink vs. polyethylene glycol with electrolyte solution as purgatives for colonoscopy – the incidence of hyponatraemia

Summary Background Polyethylene glycol 3350 plus sports drink (PEG‐SD) is a hypo‐osmotic purgative commonly used for colonoscopy, though little safety data are available. Aim To evaluate the effect of PEG‐SD on serum sodium (Na) and other electrolytes compared with PEG‐electrolyte solution (PEG‐ELS)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Alimentary pharmacology & therapeutics 2014-09, Vol.40 (6), p.610-619
Hauptverfasser:	Matro, R., Daskalakis, C., Negoianu, D., Katz, L., Henry, C., Share, M., Kastenberg, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Beverages Biological and medical sciences Cathartics - adverse effects Cathartics - therapeutic use Chlorides - blood Colonoscopy Digestive system Electrolytes - adverse effects Electrolytes - therapeutic use Female Humans Hyponatremia - blood Hyponatremia - chemically induced Male Medical sciences Middle Aged Outpatients Pharmacology. Drug treatments Polyethylene Glycols - adverse effects Polyethylene Glycols - therapeutic use Potassium - blood Sodium - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Summary Background Polyethylene glycol 3350 plus sports drink (PEG‐SD) is a hypo‐osmotic purgative commonly used for colonoscopy, though little safety data are available. Aim To evaluate the effect of PEG‐SD on serum sodium (Na) and other electrolytes compared with PEG‐electrolyte solution (PEG‐ELS). Methods We performed a single center, prospective, randomised, investigator‐blind comparison of PEG‐ELS to PEG‐SD in out‐patients undergoing colonoscopy. Laboratories were obtained at baseline and immediately before and after colonoscopy. The primary endpoint was development of hyponatraemia (Na
ISSN:	0269-2813 1365-2036
DOI:	10.1111/apt.12884