Dramatic lowering of very high Lp(a) in response to niacin
Abstract We describe a patient with markedly elevated lipoprotein(a) (Lp(a)) without any other lipid abnormalities. After a myocardial infarction, she was treated with combination of extended-release niacin and statin. An 88% reduction in Lp(a) was observed during 5 years of treatment, which is much...
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| Veröffentlicht in: | Journal of clinical lipidology 2014-07, Vol.8 (4), p.448-450 |
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| container_issue | 4 |
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| container_title | Journal of clinical lipidology |
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| creator | Li, Min, MD, PhD Saeedi, Ramesh, MD, PhD Rabkin, Simon W., MD Frohlich, Jiri, MD |
| description | Abstract We describe a patient with markedly elevated lipoprotein(a) (Lp(a)) without any other lipid abnormalities. After a myocardial infarction, she was treated with combination of extended-release niacin and statin. An 88% reduction in Lp(a) was observed during 5 years of treatment, which is much better response than usually reported. |
| doi_str_mv | 10.1016/j.jacl.2014.03.006 |
| format | Article |
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After a myocardial infarction, she was treated with combination of extended-release niacin and statin. An 88% reduction in Lp(a) was observed during 5 years of treatment, which is much better response than usually reported.</description><identifier>ISSN: 1933-2874</identifier><identifier>EISSN: 1876-4789</identifier><identifier>DOI: 10.1016/j.jacl.2014.03.006</identifier><identifier>PMID: 25110227</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Atorvastatin Calcium ; Biomarkers - metabolism ; Cardiovascular ; Coronary artery disease (CAD) ; Coronary Artery Disease - complications ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - drug therapy ; Disease-Free Survival ; Female ; Heptanoic Acids - therapeutic use ; Humans ; Hypolipidemic Agents - therapeutic use ; Lipoprotein(a) - metabolism ; Lipoprotein(a) [Lp(a)] ; Middle Aged ; Myocardial Infarction - diagnosis ; Myocardial Infarction - drug therapy ; Myocardial Infarction - etiology ; Niacin ; Niacin - therapeutic use ; Pyrroles - therapeutic use ; Risk ; Statin</subject><ispartof>Journal of clinical lipidology, 2014-07, Vol.8 (4), p.448-450</ispartof><rights>National Lipid Association</rights><rights>2014 National Lipid Association</rights><rights>Copyright © 2014 National Lipid Association. 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After a myocardial infarction, she was treated with combination of extended-release niacin and statin. 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After a myocardial infarction, she was treated with combination of extended-release niacin and statin. An 88% reduction in Lp(a) was observed during 5 years of treatment, which is much better response than usually reported.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25110227</pmid><doi>10.1016/j.jacl.2014.03.006</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1933-2874 |
| ispartof | Journal of clinical lipidology, 2014-07, Vol.8 (4), p.448-450 |
| issn | 1933-2874 1876-4789 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Atorvastatin Calcium Biomarkers - metabolism Cardiovascular Coronary artery disease (CAD) Coronary Artery Disease - complications Coronary Artery Disease - diagnosis Coronary Artery Disease - drug therapy Disease-Free Survival Female Heptanoic Acids - therapeutic use Humans Hypolipidemic Agents - therapeutic use Lipoprotein(a) - metabolism Lipoprotein(a) [Lp(a)] Middle Aged Myocardial Infarction - diagnosis Myocardial Infarction - drug therapy Myocardial Infarction - etiology Niacin Niacin - therapeutic use Pyrroles - therapeutic use Risk Statin |
| title | Dramatic lowering of very high Lp(a) in response to niacin |
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