Child's homocysteine concentration at 2 years is influenced by pregnancy vitamin B12 and folate status

Child's homocysteine concentration at 2 years is influenced by pregnancy vitamin B12 and folate status

Longitudinal studies investigating vitamin B12 and folate status of mothers and their offspring will provide a better understanding of intergenerational nutrition. During pregnancy and 2 years (2y) after delivery, we measured plasma vitamin B12 and folate concentrations in 118 women [aged (mean ± s....

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Veröffentlicht in:Journal of developmental origins of health and disease 2012-02, Vol.3 (1), p.32-38
Hauptverfasser: Lubree, H. G., Katre, P. A., Joshi, S. M., Bhat, D. S., Deshmukh, U. S., Memane, N. S., Otiv, S. R., Rush, E. C., Yajnik, C. S.
Format: Artikel
Sprache:eng
Schlagworte:
Age
Babies
Birth weight
Children & youth
Diabetes
Diet
Fetuses
Food
Homocysteine
Insulin resistance
Milk
Mothers
Nutrition research
Placenta
Pregnancy
Studies
Vegetarianism
Vitamin B
Womens health
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Zusammenfassung:Longitudinal studies investigating vitamin B12 and folate status of mothers and their offspring will provide a better understanding of intergenerational nutrition. During pregnancy and 2 years (2y) after delivery, we measured plasma vitamin B12 and folate concentrations in 118 women [aged (mean ± s.d.) 22.9 ± 3.9y] who attended a rural (n = 68) or an urban (n = 50) antenatal clinic in Pune, India. Cord blood vitamin B12 and folate were measured, and when the child was 2y total homocysteine (tHcy) was also measured. Demographic and diet measurements were recorded using standard methods. Pregnancy plasma vitamin B12 concentration at 34 weeks was low [median (25th, 75th), 115 (95, 147) pm]; 75% had low status (
ISSN:2040-1744
2040-1752
DOI:10.1017/S2040174411000602