Curable Renal Hypertension: Renin, Marker or Cause? Question Answered

I arrived in Dr Laragh’s unit in 1971 having just completed my urology residency at the University of Virginia. While there, I became interested in the role of the renin-angiotension system in the vasoconstriction that accompanied unilateral ureteral occlusion in the dog.1 In addition, I had collaborated in the laboratory of Dr Carlos Ayers working with his elegant model studying the role of the renin system in control of renal hemodynamics in the dog.2 In fact, it was Dr Ayers who facilitated my obtaining the fellowship in Laragh’s lab.