Pathophysiology and Clinical Application of the Renin System: Early Steps Toward Personalized Medicine

John H. Laragh was a visionary translational scientist, from bench to bedside. During his entire life, he worked on fitting together the complex cybernetic system of renin-angiotensin vasoconstriction and the commensurate angiotensin-aldosterone sodium-volume homeostasis and renal potassium control....

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Veröffentlicht in:American journal of hypertension 2014-08, Vol.27 (8), p.996-999
1. Verfasser: Bühler, Fritz R.
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container_title American journal of hypertension
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description John H. Laragh was a visionary translational scientist, from bench to bedside. During his entire life, he worked on fitting together the complex cybernetic system of renin-angiotensin vasoconstriction and the commensurate angiotensin-aldosterone sodium-volume homeostasis and renal potassium control. It was John Laragh who infused subpressor doses of angiotensin into man and demonstrated the attendant rise of aldosterone secretion.1
doi_str_mv 10.1093/ajh/hpu114
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identifier ISSN: 0895-7061
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source MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection
subjects Blood platelets
Blood pressure
Diuretics
History of medicine
History, 20th Century
History, 21st Century
Humans
Hypertension
Hypertension - drug therapy
Hypertension - history
Hypertension - metabolism
Hypertension - physiopathology
Laragh
Laragh, John H
Peptides
Pharmaceutical industry
Precision medicine
Precision Medicine - history
Renin - antagonists & inhibitors
Renin - blood
Renin-Angiotensin System
Sodium
Translational Medical Research - history
title Pathophysiology and Clinical Application of the Renin System: Early Steps Toward Personalized Medicine
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