The use of pulse wave velocity in predicting pre-eclampsia in high-risk women

The use of pulse wave velocity in predicting pre-eclampsia in high-risk women

In this study, we evaluated the diagnostic utility of pulse wave velocity (PWV) alone or in combination with other diagnostic markers in predicting pre-eclampsia (PE) in high-risk women. Pregnant women at high risk for PE were recruited between 22 and 26 weeks of gestation and were assessed for (a)...

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Veröffentlicht in:Hypertension research 2014-08, Vol.37 (8), p.733-740
Hauptverfasser: Katsipi, Irene, Stylianou, Kostas, Petrakis, Ioannis, Passam, Andrew, Vardaki, Eleftheria, Parthenakis, Fragkiskos, Makrygiannakis, Antonios, Daphnis, Eugene, Kyriazis, John
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Biomarkers
Calcium - urine
Female
Humans
Pre-Eclampsia - diagnosis
Predictive Value of Tests
Pregnancy
Proteinuria - urine
Pulse Wave Analysis - methods
Reference Values
Risk
Uric Acid - blood
Vascular Endothelial Growth Factor Receptor-1 - blood
Young Adult
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Zusammenfassung:In this study, we evaluated the diagnostic utility of pulse wave velocity (PWV) alone or in combination with other diagnostic markers in predicting pre-eclampsia (PE) in high-risk women. Pregnant women at high risk for PE were recruited between 22 and 26 weeks of gestation and were assessed for (a) PWV, (b) serum levels of the placental soluble fms-like tyrosine kinase 1 (sFlt-1) protein and uric acid and (c) 24-h urinary protein and calcium excretion. Sensitivities and specificities were derived from receiver operating characteristic curves. Of 118 women recruited, 11 and 10 women developed early-onset PE (
ISSN:0916-9636
1348-4214
DOI:10.1038/hr.2014.62