HLA-D Antigens in Progressive Systemic Sclerosis (Scleroderma)

HLA-D Antigens in Progressive Systemic Sclerosis (Scleroderma)

Seven unrelated patients with progressive systemic sclerosis (scleroderma) were studied for HLA-DW antigens. 4/7 possessed the DW1 antigen. This suggests that a common genetic factor, linked to the major histocompatibility complex, may be present in the majority of patients with scleroderma.

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Bibliographische Detailangaben
Veröffentlicht in:Immunological communications 1981, Vol.10 (8), p.733-740
Hauptverfasser: Dibartolomeo, A. G., Rabin, B. S., Rodnan, G. P.
Format: Artikel
Sprache:eng
Schlagworte:
Histocompatibility Antigens Class II - genetics
Histocompatibility Testing
Humans
Lymphocyte Culture Test, Mixed
Phenotype
Scleroderma, Systemic - genetics
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Zusammenfassung:Seven unrelated patients with progressive systemic sclerosis (scleroderma) were studied for HLA-DW antigens. 4/7 possessed the DW1 antigen. This suggests that a common genetic factor, linked to the major histocompatibility complex, may be present in the majority of patients with scleroderma.
ISSN:0882-0139
0090-0877
1532-4311
DOI:10.3109/08820138109051959