Secondary hematoma expansion in intracerebral hemorrhage during rivaroxaban therapy

Upon arrival of the emergency medical services, she presented awake and orientated with dysarthria and left-sided hemiplegia, with a Glasgow Coma Scale (GCS) of 15. Because her systolic blood pressure exceeded 200 mm Hg, urapidil was injected. [...]knowledge would be relevant to determine whether attempts to antagonize the anticoagulatory effect of NOAC are justified. Because specific antagonists for the NOACs are not yet available in the clinical setting [10], prothrombin concentrate or factor VIIa has been recommended based on preclinical and phase I studies, but these agents carry the risk of thromboembolic complications [11-13].