Targeting P2 receptors—current progress in treating musculoskeletal diseases

Highlights • Various P2 receptor knockout mice have alterations in the musculoskeletal system. • P2X receptor signalling is a novel target for cancer-induced bone pain. • P2X7 receptor agonists have pharmaceutical potential in treating osteoporosis. • ADP acts as a powerful osteolytic agent via P2Y1...

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Veröffentlicht in:	Current opinion in pharmacology 2014-06, Vol.16, p.122-126
Hauptverfasser:	Wang, Ning, Gartland, Alison
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone and Bones - metabolism Cartilage - metabolism Humans Internal Medicine Medical Education Musculoskeletal Diseases - metabolism Neoplasms - metabolism Receptors, Purinergic P2 - metabolism
Online-Zugang:	Volltext
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