Long-term outcomes associated with hospital acquired thrombocytopenia among patients with non–ST-segment elevation acute coronary syndrome

Background Acquired thrombocytopenia after a non–ST-segment-elevation-acute coronary syndrome (NSTE-ACS) has been associated with increased in-hospital mortality and hemorrhagic complications, but longer term outcomes are unclear. We examined the association between thrombocytopenia and long-term ou...

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Veröffentlicht in:	The American heart journal 2014-08, Vol.168 (2), p.189-196.e1
Hauptverfasser:	Vora, Amit N., MD, MPH, Chenier, Michael, MD, MPH, Schulte, Phillip J., PhD, Goodman, Shaun, MD, MSc, Peterson, Eric D., MD, MPH, Pieper, Karen, MS, Jolicoeur, Marc E., MD, MHS, Mahaffey, Kenneth W., MD, White, Harvey, MB, CHB, DSc, Wang, Tracy Y., MD, MHS, MSc
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - mortality Acute coronary syndromes Aged Cardiovascular Drug therapy Female Heart attacks Hospital Mortality Hospitalization Humans Kaplan-Meier Estimate Male Middle Aged Mortality Platelet Aggregation Inhibitors - therapeutic use Platelet Count Severity of Illness Index Thrombocytopenia - mortality Treatment Outcome
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Zusammenfassung:	Background Acquired thrombocytopenia after a non–ST-segment-elevation-acute coronary syndrome (NSTE-ACS) has been associated with increased in-hospital mortality and hemorrhagic complications, but longer term outcomes are unclear. We examined the association between thrombocytopenia and long-term outcomes after accounting for thrombocytopenia severity and discharge medication use. Methods Data from 7,435 NSTE-ACS patients enrolled in the SYNERGY trial were analyzed. Severe thrombocytopenia was defined as a nadir platelet count
ISSN:	0002-8703 1097-6744
DOI:	10.1016/j.ahj.2014.04.010