Controlled attenuation parameter for the detection and quantification of hepatic steatosis in nonalcoholic fatty liver disease

Background and Aim Controlled attenuation parameter (CAP) has been suggested as a noninvasive method for detection and quantification of hepatic steatosis. We aim to study the diagnostic performance of CAP in nonalcoholic fatty liver disease (NAFLD) patients. Methods Transient elastography was perfo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of gastroenterology and hepatology 2014-07, Vol.29 (7), p.1470-1476
Hauptverfasser: Chan, Wah-Kheong, Nik Mustapha, Nik Raihan, Mahadeva, Sanjiv
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background and Aim Controlled attenuation parameter (CAP) has been suggested as a noninvasive method for detection and quantification of hepatic steatosis. We aim to study the diagnostic performance of CAP in nonalcoholic fatty liver disease (NAFLD) patients. Methods Transient elastography was performed in consecutive NAFLD patients undergoing liver biopsy and non‐NAFLD controls. The accuracy of CAP for the detection and quantification of hepatic steatosis was assessed based on histological findings according to the Nonalcoholic Steatohepatitis Clinical Research Network Scoring System. Results Data for 101 NAFLD patients (mean age 50.3 ± 11.3 years old, 51.5% male) and 60 non‐NAFLD controls were analyzed. CAP was associated with steatosis grade (odds ratio [OR] = 29.16, P 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.12557