Controlled attenuation parameter for the detection and quantification of hepatic steatosis in nonalcoholic fatty liver disease
Background and Aim Controlled attenuation parameter (CAP) has been suggested as a noninvasive method for detection and quantification of hepatic steatosis. We aim to study the diagnostic performance of CAP in nonalcoholic fatty liver disease (NAFLD) patients. Methods Transient elastography was perfo...
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Veröffentlicht in: | Journal of gastroenterology and hepatology 2014-07, Vol.29 (7), p.1470-1476 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background and Aim
Controlled attenuation parameter (CAP) has been suggested as a noninvasive method for detection and quantification of hepatic steatosis. We aim to study the diagnostic performance of CAP in nonalcoholic fatty liver disease (NAFLD) patients.
Methods
Transient elastography was performed in consecutive NAFLD patients undergoing liver biopsy and non‐NAFLD controls. The accuracy of CAP for the detection and quantification of hepatic steatosis was assessed based on histological findings according to the Nonalcoholic Steatohepatitis Clinical Research Network Scoring System.
Results
Data for 101 NAFLD patients (mean age 50.3 ± 11.3 years old, 51.5% male) and 60 non‐NAFLD controls were analyzed. CAP was associated with steatosis grade (odds ratio [OR] = 29.16, P |
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ISSN: | 0815-9319 1440-1746 |
DOI: | 10.1111/jgh.12557 |