Treatment of canine asthma by high selective vagotomy

Objectives This study evaluated the effect of high selective bilateral vagotomy of hilus pulmonis with video-assisted thoracoscopy on asthma. Methods Eight dogs with skin sensitive to Ascaris suum antigens were randomly divided into groups A and B. Asthma was induced by aerosol inhalation of A suum...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2014-08, Vol.148 (2), p.683-689
Hauptverfasser:	Liu, Rui, MD, Song, Jiangping, MD, Li, Hui, MD, Wu, Ziheng, MD, Chen, Huiguo, MD, Wu, Weibin, MD, Gu, Lijia, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Animals Antigens, Helminth - immunology Ascaris suum - immunology Asthma - blood Asthma - immunology Asthma - physiopathology Asthma - prevention & control Bronchial Hyperreactivity - blood Bronchial Hyperreactivity - immunology Bronchial Hyperreactivity - physiopathology Bronchial Hyperreactivity - prevention & control Cardiothoracic Surgery Disease Models, Animal Dogs Inflammation Mediators - blood Inhalation Exposure Lung - immunology Lung - innervation Lung Compliance Pressure Respiratory Rate Thoracic Surgery, Video-Assisted Tidal Volume Time Factors Vagotomy - methods
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Beschreibung
Zusammenfassung:	Objectives This study evaluated the effect of high selective bilateral vagotomy of hilus pulmonis with video-assisted thoracoscopy on asthma. Methods Eight dogs with skin sensitive to Ascaris suum antigens were randomly divided into groups A and B. Asthma was induced by aerosol inhalation of A suum antigens. Respiratory rate and peak airway pressure were significantly increased ( P
ISSN:	0022-5223 1097-685X
DOI:	10.1016/j.jtcvs.2013.12.041