Modeling the Effect of Different Vaccine Effectiveness Estimates on the Number of Vaccine-Prevented Influenza-Associated Hospitalizations in Older Adults

We compared influenza vaccine–prevented hospitalizations in adults aged ≥65 years for a range of hypothetical effectiveness estimates. During 2012–2013, a vaccine with 10% effectiveness (66% coverage) would have averted approximately 13 000 hospitalizations, and a vaccine with 40% effectiveness woul...

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Veröffentlicht in:	Clinical infectious diseases 2014-08, Vol.59 (3), p.406-409
Hauptverfasser:	Fry, Alicia M., Kim, Inkyu K., Reed, Carrie, Thompson, Mark, Chaves, Sandra S., Finelli, Lyn, Bresee, Joseph
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age groups Aged Aged, 80 and over Biological and medical sciences Breeding seasons BRIEF REPORT Comparative studies Disease models Effectiveness studies Hospitalization Hospitalization - statistics & numerical data Human viral diseases Humans Inactivated vaccines Infectious diseases Influenza Influenza vaccines Influenza Vaccines - immunology Influenza, Human - immunology Influenza, Human - prevention & control Medical sciences Models, Theoretical Older adults Older people Preventive medicine Treatment Outcome Vaccination Vaccines Viral diseases Viral diseases of the respiratory system and ent viral diseases
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Zusammenfassung:	We compared influenza vaccine–prevented hospitalizations in adults aged ≥65 years for a range of hypothetical effectiveness estimates. During 2012–2013, a vaccine with 10% effectiveness (66% coverage) would have averted approximately 13 000 hospitalizations, and a vaccine with 40% effectiveness would have averted approximately 60 000 hospitalizations. Annual vaccination is merited in this vulnerable population.
ISSN:	1058-4838 1537-6591
DOI:	10.1093/cid/ciu328