Cumulative Effects from Repeated Exposures to Ultraviolet Radiation
Repeated exposures to subliminal doses of UVR, given at 24-hr intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to sub...
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| Veröffentlicht in: | J. Invest. Dermatol.; (United States) 1981-05, Vol.76 (5), p.352-355 |
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| container_end_page | 355 |
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| container_title | J. Invest. Dermatol.; (United States) |
| container_volume | 76 |
| creator | Kaidbey, Kays H. Kligman, Albert M. |
| description | Repeated exposures to subliminal doses of UVR, given at 24-hr intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. These findings provide quantitative evidence for the cumulative nature of acute UVR damage in human skin. |
| doi_str_mv | 10.1111/1523-1747.ep12520007 |
| format | Article |
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At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. 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Invest. Dermatol.; (United States)</title><addtitle>J Invest Dermatol</addtitle><description>Repeated exposures to subliminal doses of UVR, given at 24-hr intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. These findings provide quantitative evidence for the cumulative nature of acute UVR damage in human skin.</description><subject>560151 - Radiation Effects on Animals- Man</subject><subject>Adolescent</subject><subject>Adult</subject><subject>ANTICOAGULANTS</subject><subject>BIOLOGICAL EFFECTS</subject><subject>BIOLOGICAL RADIATION EFFECTS</subject><subject>BODY</subject><subject>COUMARINS</subject><subject>Dose-Response Relationship, Drug</subject><subject>Dose-Response Relationship, Radiation</subject><subject>DOSE-RESPONSE RELATIONSHIPS</subject><subject>DOSES</subject><subject>DRUGS</subject><subject>ELECTROMAGNETIC RADIATION</subject><subject>ERYTHEMA</subject><subject>Erythema - etiology</subject><subject>Female</subject><subject>FRACTIONATED IRRADIATION</subject><subject>HEMATOLOGIC AGENTS</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>Humans</subject><subject>IRRADIATION</subject><subject>Male</subject><subject>Methoxsalen - adverse effects</subject><subject>ORGANIC COMPOUNDS</subject><subject>ORGANIC OXYGEN COMPOUNDS</subject><subject>ORGANS</subject><subject>PSORALEN</subject><subject>RADIATION DOSES</subject><subject>RADIATION EFFECTS</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. 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MAT</subject><subject>RADIATIONS</subject><subject>RADIOINDUCTION</subject><subject>RADIOSENSITIVITY EFFECTS</subject><subject>SKIN</subject><subject>Skin - drug effects</subject><subject>Skin - radiation effects</subject><subject>SYMPTOMS</subject><subject>THRESHOLD DOSE</subject><subject>ULTRAVIOLET RADIATION</subject><subject>Ultraviolet Rays - adverse effects</subject><issn>0022-202X</issn><issn>1523-1747</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVp2G6S_oMWTA-5eaNP27oUyrL5gEAgZCE3oZXGVMW2XElemn9fmV12b5nLwLzvO8w8CH0jeEVy3RJBWUlqXq9gJFRQjHH9CS1P489oiTGlJcX07Qu6jPEPxqTiolmgRU2p5LRaovV66qdOJ7eHYtO2YFIs2uD74gVG0Alssfk3-jgFiEXyxbZLQe-d7yAVL9q6HPTDNbpodRfh67Ffoe3d5nX9UD493z-ufz2VhjcslYYIxjTjWre4IkxawqU2jdlRCQ0nRoOxO8lEje3OMmYoSKmxkVhwrpkw7Ar9OOz1MTkVjUtgfhs_DPlqJSpWcUyy6eZgGoP_O0FMqnfRQNfpAfwUFRFcMM6rbOQHowk-xgCtGoPrdXhXBKsZsJpJqpmkOgPOse_H_dOuB3sKHYme9UGnTO2ki4qISjZZ_3nQIZPaOwjzIzAYsC7Mf1jvPj7gP0Huk8Q</recordid><startdate>198105</startdate><enddate>198105</enddate><creator>Kaidbey, Kays H.</creator><creator>Kligman, Albert M.</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope><scope>OTOTI</scope></search><sort><creationdate>198105</creationdate><title>Cumulative Effects from Repeated Exposures to Ultraviolet Radiation</title><author>Kaidbey, Kays H. ; Kligman, Albert M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-c1533a34aaf06139d149ac8cb29e841caecdb93570dbd33c2e99a0c90544a35c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>560151 - Radiation Effects on Animals- Man</topic><topic>Adolescent</topic><topic>Adult</topic><topic>ANTICOAGULANTS</topic><topic>BIOLOGICAL EFFECTS</topic><topic>BIOLOGICAL RADIATION EFFECTS</topic><topic>BODY</topic><topic>COUMARINS</topic><topic>Dose-Response Relationship, Drug</topic><topic>Dose-Response Relationship, Radiation</topic><topic>DOSE-RESPONSE RELATIONSHIPS</topic><topic>DOSES</topic><topic>DRUGS</topic><topic>ELECTROMAGNETIC RADIATION</topic><topic>ERYTHEMA</topic><topic>Erythema - etiology</topic><topic>Female</topic><topic>FRACTIONATED IRRADIATION</topic><topic>HEMATOLOGIC AGENTS</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>Humans</topic><topic>IRRADIATION</topic><topic>Male</topic><topic>Methoxsalen - adverse effects</topic><topic>ORGANIC COMPOUNDS</topic><topic>ORGANIC OXYGEN COMPOUNDS</topic><topic>ORGANS</topic><topic>PSORALEN</topic><topic>RADIATION DOSES</topic><topic>RADIATION EFFECTS</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. 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A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. These findings provide quantitative evidence for the cumulative nature of acute UVR damage in human skin.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7229426</pmid><doi>10.1111/1523-1747.ep12520007</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0022-202X |
| ispartof | J. Invest. Dermatol.; (United States), 1981-05, Vol.76 (5), p.352-355 |
| issn | 0022-202X 1523-1747 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | 560151 - Radiation Effects on Animals- Man Adolescent Adult ANTICOAGULANTS BIOLOGICAL EFFECTS BIOLOGICAL RADIATION EFFECTS BODY COUMARINS Dose-Response Relationship, Drug Dose-Response Relationship, Radiation DOSE-RESPONSE RELATIONSHIPS DOSES DRUGS ELECTROMAGNETIC RADIATION ERYTHEMA Erythema - etiology Female FRACTIONATED IRRADIATION HEMATOLOGIC AGENTS HETEROCYCLIC COMPOUNDS Humans IRRADIATION Male Methoxsalen - adverse effects ORGANIC COMPOUNDS ORGANIC OXYGEN COMPOUNDS ORGANS PSORALEN RADIATION DOSES RADIATION EFFECTS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIATIONS RADIOINDUCTION RADIOSENSITIVITY EFFECTS SKIN Skin - drug effects Skin - radiation effects SYMPTOMS THRESHOLD DOSE ULTRAVIOLET RADIATION Ultraviolet Rays - adverse effects |
| title | Cumulative Effects from Repeated Exposures to Ultraviolet Radiation |
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