Cumulative Effects from Repeated Exposures to Ultraviolet Radiation

Cumulative Effects from Repeated Exposures to Ultraviolet Radiation

Repeated exposures to subliminal doses of UVR, given at 24-hr intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to sub...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J. Invest. Dermatol.; (United States) 1981-05, Vol.76 (5), p.352-355
Hauptverfasser: Kaidbey, Kays H., Kligman, Albert M.
Format: Artikel
Sprache:eng
Schlagworte:
560151 - Radiation Effects on Animals- Man
Adolescent
Adult
ANTICOAGULANTS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
COUMARINS
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
DOSE-RESPONSE RELATIONSHIPS
DOSES
DRUGS
ELECTROMAGNETIC RADIATION
ERYTHEMA
Erythema - etiology
Female
FRACTIONATED IRRADIATION
HEMATOLOGIC AGENTS
HETEROCYCLIC COMPOUNDS
Humans
IRRADIATION
Male
Methoxsalen - adverse effects
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
PSORALEN
RADIATION DOSES
RADIATION EFFECTS
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
RADIATIONS
RADIOINDUCTION
RADIOSENSITIVITY EFFECTS
SKIN
Skin - drug effects
Skin - radiation effects
SYMPTOMS
THRESHOLD DOSE
ULTRAVIOLET RADIATION
Ultraviolet Rays - adverse effects
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Repeated exposures to subliminal doses of UVR, given at 24-hr intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. These findings provide quantitative evidence for the cumulative nature of acute UVR damage in human skin.
ISSN:0022-202X
1523-1747
DOI:10.1111/1523-1747.ep12520007