Evaluation of the hyperbranched polymer Hybrane H1500 for production of matricial controlled-release particles by hot-melt extrusion

Evaluation of the hyperbranched polymer Hybrane H1500 for production of matricial controlled-release particles by hot-melt extrusion

Extrudates of the hyperbranched polymer Hybrane H1500 prepared by hot melt extrusion, with five particle sizes (from

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Bibliographische Detailangaben
Veröffentlicht in:International journal of pharmaceutics 2014-01, Vol.461 (1-2), p.469-477
Hauptverfasser: Raviña-Eirín, Elena, Sánchez-Rodríguez, Blanca, Gómez-Amoza, Jose Luis, Martínez-Pacheco, Ramón
Format: Artikel
Sprache:eng
Schlagworte:
Acetaminophen
Acetaminophen - administration & dosage
Acetaminophen - chemistry
Caffeine
Caffeine - administration & dosage
Caffeine - chemistry
Chemistry, Pharmaceutical - methods
Controlled release particles
Crystallization
Cyclohexanecarboxylic Acids - chemistry
Delayed-Action Preparations
Drug Carriers - chemistry
Drug Compounding - methods
Drug Stability
Hot melt extrusion
Hot Temperature
Hybrane H1500
Hyperbranched polymer
Kinetics
Particle Size
Polyesters - chemistry
Porosity
Propanolamines - chemistry
Solubility
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Beschreibung
Zusammenfassung:Extrudates of the hyperbranched polymer Hybrane H1500 prepared by hot melt extrusion, with five particle sizes (from
ISSN:0378-5173
1873-3476
DOI:10.1016/j.ijpharm.2013.12.019