Difference gel electrophoresis DIGE
Proteomics offers powerful technologies to assist in the discovery of targets for novel therapeutic agents, by allowing the investigation of changes in protein state between control and diseased tissue and biofluids. Difference gel electrophoresis coupled with mass spectrometry (DIGE/MS) is a techno...
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| Veröffentlicht in: | Drug discovery today. Technologies 2006, Vol.3 (3), p.347-353 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Proteomics offers powerful technologies to assist in the discovery of targets for novel therapeutic agents, by allowing the investigation of changes in protein state between control and diseased tissue and biofluids. Difference gel electrophoresis coupled with mass spectrometry (DIGE/MS) is a technology used within proteomics that has demonstrated technical robustness and associated statistical confidence to enable successful identification of therapeutic targets.
Anne-Claude Gavin – EMBL, Heidelberg, Germany
Albert Heck – Utrecht University, Utrecht, The Netherlands |
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| ISSN: | 1740-6749 1740-6749 |
| DOI: | 10.1016/j.ddtec.2006.09.013 |