Paper Microfluidics Goes Digital

The first example of so‐called “digital microfluidics” (DMF) implemented on paper by inkjet printing is reported. A sandwich enzyme‐linked immunosorbent assay (ELISA) is demonstrated as an example of a complex, multistep protocol that would be difficult to achieve with capillary‐driven paper microfluidics. Furthermore, it is shown that paper‐based DMF devices have comparable performance to traditional photolithographically patterned DMF devices at a fraction of the cost.