Broad-Spectrum Antiviral Property of Polyoxometalate Localized on a Cell Surface

Cs2K4Na[SiW9Nb3O40] has broad antiviral ability including anti-Influenza A, -Influenza B, -HSV-1, -HSV-2, -HIV-1, and -HBV. A series of antivirus and/or biochemical experiments and X-ray nanotomography analysis confirm that this kind of broad-spectrum antiviral property is mainly due to its localiz...

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Veröffentlicht in:	ACS applied materials & interfaces 2014-06, Vol.6 (12), p.9785-9789
Hauptverfasser:	Wang, Juan, Liu, Yang, Xu, Kun, Qi, Yanfei, Zhong, Jun, Zhang, Kai, Li, Juan, Wang, Enbo, Wu, Ziyu, Kang, Zhenhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - chemistry Antiviral Agents - pharmacology Hep G2 Cells - chemistry Hep G2 Cells - virology Humans Surface Properties Tungsten Compounds - chemistry Tungsten Compounds - pharmacology Viruses - drug effects
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Beschreibung
Zusammenfassung:	Cs2K4Na[SiW9Nb3O40] has broad antiviral ability including anti-Influenza A, -Influenza B, -HSV-1, -HSV-2, -HIV-1, and -HBV. A series of antivirus and/or biochemical experiments and X-ray nanotomography analysis confirm that this kind of broad-spectrum antiviral property is mainly due to its localization on the cell surface.
ISSN:	1944-8244 1944-8252
DOI:	10.1021/am502193f