The antibacterial properties of sulfur containing flavonoids

The antibacterial properties of sulfur containing flavonoids

Some dithiocarbamic esters bearing a flavanone backbone, as well as their corresponding 1,3-dithiolium salts were tested against Staphylococcus aureus and Escherichia coli. The 1,3-dithiolium tricyclic flavonoids display good inhibitory properties against both Gram-positive and Gram-negative pathoge...

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Veröffentlicht in:Bioorganic & medicinal chemistry letters 2014-05, Vol.24 (10), p.2315-2318
Hauptverfasser: Bahrin, Lucian G., Apostu, Mircea O., Birsa, Lucian M., Stefan, Marius
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - pharmacology
Antibacterial activity
Dithiocarbamates
Dithiolium salts
Escherichia coli
Escherichia coli - drug effects
Flavonoids
Flavonoids - pharmacology
Microbial Sensitivity Tests
Staphylococcus aureus
Staphylococcus aureus - drug effects
Sulfur Compounds - pharmacology
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Beschreibung
Zusammenfassung:Some dithiocarbamic esters bearing a flavanone backbone, as well as their corresponding 1,3-dithiolium salts were tested against Staphylococcus aureus and Escherichia coli. The 1,3-dithiolium tricyclic flavonoids display good inhibitory properties against both Gram-positive and Gram-negative pathogens.
ISSN:0960-894X
1464-3405
DOI:10.1016/j.bmcl.2014.03.071