Pseudomonas aeruginosa O-polysaccharide-protein conjugate vaccines

Pseudomonas aeruginosa O-polysaccharide-protein conjugate vaccines

Our studies toward vaccine development have been aimed at synthesizing a conjugate vaccine capable of eliciting both an antitoxic and an anti-LPS immune response. To accomplish this, we took advantage of the fact that serologically reactive O-antigenic determinants (hereafter termed O-polysaccharide...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology newsletter 1988, Vol.9 (7), p.113-115
1. Verfasser: Cryz, S.J.
Format: Artikel
Sprache:eng
Schlagworte:
reviews
vaccines
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Our studies toward vaccine development have been aimed at synthesizing a conjugate vaccine capable of eliciting both an antitoxic and an anti-LPS immune response. To accomplish this, we took advantage of the fact that serologically reactive O-antigenic determinants (hereafter termed O-polysaccharide (O-PS)) could be isolated from LPS free of the toxic lipid A portion of the molecule.
ISSN:0197-1859
DOI:10.1016/0197-1859(88)90043-X