Effect of Alloxan on the Activity of Cell Surface Galactosyltransferases in Rat Pancreatic Islet

Effect of Alloxan on the Activity of Cell Surface Galactosyltransferases in Rat Pancreatic Islet

Maier and Pfeiffer suggested that sialic acid, possibly attached to membrane proteins of the islets, might play an important role in glucose-induced insulin release. Glycosyltransferase have been found to locate on the surface of various cells and to function in cellular recognition. A study of chan...

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Veröffentlicht in:Hormone and metabolic research 1981-01, Vol.13 (1), p.59-60
Hauptverfasser: Tsumura, Y., Murakoso, K., Kagawa, S., Matsuoka, A.
Format: Artikel
Sprache:eng
Schlagworte:
alloxan
cell surface
galactosyltransferases
pancreas
rats
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Zusammenfassung:Maier and Pfeiffer suggested that sialic acid, possibly attached to membrane proteins of the islets, might play an important role in glucose-induced insulin release. Glycosyltransferase have been found to locate on the surface of various cells and to function in cellular recognition. A study of change in glycosyltransferases activities on the cell surface of islets should cast light on the mechanism of alloxan action on the cell membranes.
ISSN:0018-5043
1439-4286
DOI:10.1055/s-2007-1019169