Silicon Nanowire-Based Fluorescent Nanosensor for Complexed Cu2+ and its Bioapplications

A silicon nanowires (SiNWs)-based fluorescent sensor for complexed Cu2+ was realized. High sensitivity and selectivity of the present sensor facilitate its bioapplications. The sensor was successfully used to detect the Cu2+ in liver extract. Meanwhile, real-time and in situ monitoring of Cu2+ relea...

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Veröffentlicht in:	Nano letters 2014-06, Vol.14 (6), p.3124-3129
Hauptverfasser:	Miao, Rong, Mu, Lixuan, Zhang, Hongyan, She, Guangwei, Zhou, Bingjiang, Xu, Haitao, Wang, Pengfei, Shi, Wensheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques - methods Copper - analysis Copper - metabolism Cross-disciplinary physics: materials science rheology Exact sciences and technology General equipment and techniques HeLa Cells Humans Instruments, apparatus, components and techniques common to several branches of physics and astronomy Materials science Nanocrystalline materials Nanoscale materials and structures: fabrication and characterization Nanowires - chemistry Physics Quantum wires Sensors (chemical, optical, electrical, movement, gas, etc.) remote sensing Silicon - chemistry Spectrometry, Fluorescence
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Beschreibung
Zusammenfassung:	A silicon nanowires (SiNWs)-based fluorescent sensor for complexed Cu2+ was realized. High sensitivity and selectivity of the present sensor facilitate its bioapplications. The sensor was successfully used to detect the Cu2+ in liver extract. Meanwhile, real-time and in situ monitoring of Cu2+ released from apoptotic HeLa cell was performed using the as-prepared SiNW arrays-based sensor. These results indicate that the present SiNWs-based sensor would be of potential applications in revealing the physiological and pathological roles of Cu2+.
ISSN:	1530-6984 1530-6992
DOI:	10.1021/nl500276x