Characterization of the classical biological false-positive reaction in the serological test for syphilis in the modern era

To characterize the CBFP reaction in the modern era, we analyzed the results of parallel rapid plasma reagin (RPR) and Treponema pallidum particle agglutination (TPPA) tests from a total of 63,765 blood samples obtained at Zhongshan Hospital in the Medical College of Xiamen University from May 2008...

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Veröffentlicht in:	International immunopharmacology 2014-06, Vol.20 (2), p.331-336
Hauptverfasser:	Liu, Fan, Liu, Li-Li, Guo, Xiao-Jing, Xi, Ya, Lin, Li-Rong, Zhang, Hui-Lin, Huang, Song-Jie, Chen, Yu-Yan, Zhang, Ya-Feng, Zhang, Qiao, Huang, Ge-Ling, Tong, Man-Li, Jiang, Jie, Yang, Tian-Ci
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged, 80 and over Biological false positive China Comorbidity False Positive Reactions Female Follow-Up Studies Humans Male Nontreponemal antibody test Rapid plasma reagin Risk Factors Syphilis Syphilis - diagnosis Syphilis - epidemiology Syphilis Serodiagnosis - methods Syphilis Serodiagnosis - statistics & numerical data Treponema pallidum Treponema pallidum - physiology Treponema pallidum particle agglutination Young Adult
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Zusammenfassung:	To characterize the CBFP reaction in the modern era, we analyzed the results of parallel rapid plasma reagin (RPR) and Treponema pallidum particle agglutination (TPPA) tests from a total of 63,765 blood samples obtained at Zhongshan Hospital in the Medical College of Xiamen University from May 2008 to February 2013. Among the 63,765 tested blood samples, 206 (0.32%) had the CBFP reaction. In multivariate analysis, an increased likelihood of the CBFP reaction was associated with female subjects, subjects ≥80years old, and subjects between 16 and 35years old (P
ISSN:	1567-5769 1878-1705
DOI:	10.1016/j.intimp.2014.03.011