Daily Energy Expenditure, Cardiorespiratory Fitness and Glycaemic Control in People with Type 1 Diabetes: e97534

Objective Encouraging daily physical activity improves cardiorespiratory fitness and many cardiovascular risk factors. However, increasing physical activity often creates a challenge for people with type 1 diabetes, because of difficulties maintaining euglycemia in the face of altered food intake and adjustments to insulin doses. Our aim was to examine the triangular relationship between glucose control measured by continuous glucose monitoring system (CGMS), objective measures of total daily energy expenditure (TEE) recorded by a multi-sensory monitoring device, and cardiorespiratory fitness (CRF), in free-living subjects with type 1 diabetes. Research Design and Methods Twenty-three individuals (12 women) with type 1 diabetes who were free from micro- and macrovascular complications were recruited. TEE and glucose control were monitored simultaneously for up to 12 days, using a multi-sensory device and CGMS respectively. CRF was recorded as V02 max from a maximal treadmill test with the Bruce protocol. Results Subjects (mean plus or minus SD) were aged 37 plus or minus 11 years, with BMI = 26.5 plus or minus 5.1 kg.m-2, HbA1c = 7.7 plus or minus 1.3% (61 plus or minus 14 mmol/mol) and V02 max (ml.min-1.kg-1) = 39.9 plus or minus 8.4 (range 22.4 - 58.6). TEE (36.3 plus or minus 5.5 kcal.kg-1.day-1) was strongly associated with CRF(39.9 plus or minus 8.4 ml.min-1.kg-1) independently of sex (r = 0.63, p