Interlaboratory testing of Insent e-tongues
[Display omitted] The first interlaboratory testing of electronic taste sensing systems was performed within five participating centers, each working with the Insent (Insent Inc., Atsugi-Shi, Japan) e-tongue. Preparation of the samples for the comprised four experiments, shipping of the samples and...
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| Veröffentlicht in: | International journal of pharmaceutics 2014-08, Vol.469 (2), p.228-237 |
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| container_end_page | 237 |
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| container_issue | 2 |
| container_start_page | 228 |
| container_title | International journal of pharmaceutics |
| container_volume | 469 |
| creator | Pein, Miriam Gondongwe, Xolani Dereck Habara, Masaaki Winzenburg, Gesine |
| description | [Display omitted]
The first interlaboratory testing of electronic taste sensing systems was performed within five participating centers, each working with the Insent (Insent Inc., Atsugi-Shi, Japan) e-tongue. Preparation of the samples for the comprised four experiments, shipping of the samples and evaluation of the results was performed at the University of Duesseldorf. The sensitivity (in this case the difference between lowest and highest sensor response) and slope of the regression line values, obtained within Experiment 1 and 2, have been found to serve as applicable evaluation criterions for interlaboratory comparability. Modified sensor responses could be attributed to aged sensors, but did not influence the results of either Experiment 3, dealing with the evaluation of film formulations, or Experiment 4, dealing with the evaluation of minitablet formulations, in a great amount. Presented PCA Score and Loading Scatter Plots as well as Euclidean distance patterns based on the raw sensor responses confirmed the comparable performance of Insent e-tongues of the participating centers. |
| doi_str_mv | 10.1016/j.ijpharm.2014.02.036 |
| format | Article |
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The first interlaboratory testing of electronic taste sensing systems was performed within five participating centers, each working with the Insent (Insent Inc., Atsugi-Shi, Japan) e-tongue. Preparation of the samples for the comprised four experiments, shipping of the samples and evaluation of the results was performed at the University of Duesseldorf. The sensitivity (in this case the difference between lowest and highest sensor response) and slope of the regression line values, obtained within Experiment 1 and 2, have been found to serve as applicable evaluation criterions for interlaboratory comparability. Modified sensor responses could be attributed to aged sensors, but did not influence the results of either Experiment 3, dealing with the evaluation of film formulations, or Experiment 4, dealing with the evaluation of minitablet formulations, in a great amount. Presented PCA Score and Loading Scatter Plots as well as Euclidean distance patterns based on the raw sensor responses confirmed the comparable performance of Insent e-tongues of the participating centers.</description><identifier>ISSN: 0378-5173</identifier><identifier>EISSN: 1873-3476</identifier><identifier>DOI: 10.1016/j.ijpharm.2014.02.036</identifier><identifier>PMID: 24560640</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Dimenhydrinate - chemistry ; Electrical Equipment and Supplies ; Electronic taste sensing system ; EuPFi ; Excipients - chemistry ; Interlaboratory ; Laboratories ; Potassium Chloride - chemistry ; Sensor age ; Sensor performance ; Tablets ; Taste ; Technology, Pharmaceutical - instrumentation ; Tongue</subject><ispartof>International journal of pharmaceutics, 2014-08, Vol.469 (2), p.228-237</ispartof><rights>2014</rights><rights>Copyright © 2014. Published by Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-88ac71b868cce7a3fdef43ef6120fe43e001038ab00b2fa1fce1fc47be1f11f33</citedby><cites>FETCH-LOGICAL-c431t-88ac71b868cce7a3fdef43ef6120fe43e001038ab00b2fa1fce1fc47be1f11f33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ijpharm.2014.02.036$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24560640$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pein, Miriam</creatorcontrib><creatorcontrib>Gondongwe, Xolani Dereck</creatorcontrib><creatorcontrib>Habara, Masaaki</creatorcontrib><creatorcontrib>Winzenburg, Gesine</creatorcontrib><title>Interlaboratory testing of Insent e-tongues</title><title>International journal of pharmaceutics</title><addtitle>Int J Pharm</addtitle><description>[Display omitted]
The first interlaboratory testing of electronic taste sensing systems was performed within five participating centers, each working with the Insent (Insent Inc., Atsugi-Shi, Japan) e-tongue. Preparation of the samples for the comprised four experiments, shipping of the samples and evaluation of the results was performed at the University of Duesseldorf. The sensitivity (in this case the difference between lowest and highest sensor response) and slope of the regression line values, obtained within Experiment 1 and 2, have been found to serve as applicable evaluation criterions for interlaboratory comparability. Modified sensor responses could be attributed to aged sensors, but did not influence the results of either Experiment 3, dealing with the evaluation of film formulations, or Experiment 4, dealing with the evaluation of minitablet formulations, in a great amount. Presented PCA Score and Loading Scatter Plots as well as Euclidean distance patterns based on the raw sensor responses confirmed the comparable performance of Insent e-tongues of the participating centers.</description><subject>Dimenhydrinate - chemistry</subject><subject>Electrical Equipment and Supplies</subject><subject>Electronic taste sensing system</subject><subject>EuPFi</subject><subject>Excipients - chemistry</subject><subject>Interlaboratory</subject><subject>Laboratories</subject><subject>Potassium Chloride - chemistry</subject><subject>Sensor age</subject><subject>Sensor performance</subject><subject>Tablets</subject><subject>Taste</subject><subject>Technology, Pharmaceutical - instrumentation</subject><subject>Tongue</subject><issn>0378-5173</issn><issn>1873-3476</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMoWqs_QelSkBlvHvNwJVJ8FApudB0ymZuaYWZSk1Tovzel1a2Ly72Lc-7hfIRcUcgp0PKuy223_lR-yBlQkQPLgZdHZELrimdcVOUxmQCv6qygFT8j5yF0AFAyyk_JGRNFCaWACbldjBF9rxrnVXR-O4sYoh1XM2dmizHgGGeYRTeuNhguyIlRfcDLw56Sj-en9_lrtnx7Wcwfl5kWnMasrpWuaFOXtdZYKW5aNIKjKSkDg-kCoMBr1QA0zChqNKYRVZMWpYbzKbnZ_11795Vyoxxs0Nj3akS3CZIWqd-9YAVL0mIv1d6F4NHItbeD8ltJQe44yU4eOMkdJwlMJk7Jd32I2DQDtn-uXzBJ8LAXYCr6bdHLoC2OGlvrUUfZOvtPxA9nkXvm</recordid><startdate>20140805</startdate><enddate>20140805</enddate><creator>Pein, Miriam</creator><creator>Gondongwe, Xolani Dereck</creator><creator>Habara, Masaaki</creator><creator>Winzenburg, Gesine</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140805</creationdate><title>Interlaboratory testing of Insent e-tongues</title><author>Pein, Miriam ; Gondongwe, Xolani Dereck ; Habara, Masaaki ; Winzenburg, Gesine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-88ac71b868cce7a3fdef43ef6120fe43e001038ab00b2fa1fce1fc47be1f11f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Dimenhydrinate - chemistry</topic><topic>Electrical Equipment and Supplies</topic><topic>Electronic taste sensing system</topic><topic>EuPFi</topic><topic>Excipients - chemistry</topic><topic>Interlaboratory</topic><topic>Laboratories</topic><topic>Potassium Chloride - chemistry</topic><topic>Sensor age</topic><topic>Sensor performance</topic><topic>Tablets</topic><topic>Taste</topic><topic>Technology, Pharmaceutical - instrumentation</topic><topic>Tongue</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pein, Miriam</creatorcontrib><creatorcontrib>Gondongwe, Xolani Dereck</creatorcontrib><creatorcontrib>Habara, Masaaki</creatorcontrib><creatorcontrib>Winzenburg, Gesine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of pharmaceutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pein, Miriam</au><au>Gondongwe, Xolani Dereck</au><au>Habara, Masaaki</au><au>Winzenburg, Gesine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interlaboratory testing of Insent e-tongues</atitle><jtitle>International journal of pharmaceutics</jtitle><addtitle>Int J Pharm</addtitle><date>2014-08-05</date><risdate>2014</risdate><volume>469</volume><issue>2</issue><spage>228</spage><epage>237</epage><pages>228-237</pages><issn>0378-5173</issn><eissn>1873-3476</eissn><abstract>[Display omitted]
The first interlaboratory testing of electronic taste sensing systems was performed within five participating centers, each working with the Insent (Insent Inc., Atsugi-Shi, Japan) e-tongue. Preparation of the samples for the comprised four experiments, shipping of the samples and evaluation of the results was performed at the University of Duesseldorf. The sensitivity (in this case the difference between lowest and highest sensor response) and slope of the regression line values, obtained within Experiment 1 and 2, have been found to serve as applicable evaluation criterions for interlaboratory comparability. Modified sensor responses could be attributed to aged sensors, but did not influence the results of either Experiment 3, dealing with the evaluation of film formulations, or Experiment 4, dealing with the evaluation of minitablet formulations, in a great amount. Presented PCA Score and Loading Scatter Plots as well as Euclidean distance patterns based on the raw sensor responses confirmed the comparable performance of Insent e-tongues of the participating centers.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>24560640</pmid><doi>10.1016/j.ijpharm.2014.02.036</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0378-5173 |
| ispartof | International journal of pharmaceutics, 2014-08, Vol.469 (2), p.228-237 |
| issn | 0378-5173 1873-3476 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Dimenhydrinate - chemistry Electrical Equipment and Supplies Electronic taste sensing system EuPFi Excipients - chemistry Interlaboratory Laboratories Potassium Chloride - chemistry Sensor age Sensor performance Tablets Taste Technology, Pharmaceutical - instrumentation Tongue |
| title | Interlaboratory testing of Insent e-tongues |
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