Significant improvement in mild acne following a twice daily application for 6 weeks of an acidic cleansing product (pH 4)

Summary Background Cleansing products for acne should remove excessive sebum, reduce acne‐related bacteria and improve inflammation. Aims The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris. Methods Sixty patients were recruite...

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Veröffentlicht in:	Journal of cosmetic dermatology 2014-06, Vol.13 (2), p.103-108
Hauptverfasser:	Abels, Christoph, Reich, Hubert, Knie, Ulrich, Werdier, Dieter, Lemmnitz, Gunter
Format:	Artikel
Sprache:	eng
Schlagworte:	acne vulgaris Acne Vulgaris - drug therapy Adolescent Adult AHA antibacterial clinical trial Detergents - administration & dosage Detergents - adverse effects Detergents - chemistry Female Glycolates - administration & dosage Glycolates - adverse effects Glycolates - chemistry glycolic acid Humans Hydrogen-Ion Concentration Male Middle Aged P. acnes Severity of Illness Index Time Factors Young Adult
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Zusammenfassung:	Summary Background Cleansing products for acne should remove excessive sebum, reduce acne‐related bacteria and improve inflammation. Aims The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris. Methods Sixty patients were recruited for this open uncontrolled clinical trial. The tested product was exclusively applied twice a day for 6 weeks. The efficacy was judged by a dermatologist according to the Leeds score after 3 and 6 weeks. In addition, efficacy and tolerability were judged subjectively by physician and patients. Results Mild acne improved significantly after 6 weeks (baseline: 0.699 vs. day 42: 0.602; P
ISSN:	1473-2130 1473-2165
DOI:	10.1111/jocd.12086