SYNERGISTIC EFFECT OF THIAMPHENICOL AND CEPHALOTHIN ON BACTEROIDES FRAGILIS

SYNERGISTIC EFFECT OF THIAMPHENICOL AND CEPHALOTHIN ON BACTEROIDES FRAGILIS

Synergistic effect of thiamphenicol (TP) and cephalothin (CET) on Bacteroides fragilis was proved in vitro. Especially its effect was much clear on B. fragilis which is possible to produce β-lactamase. Synergistic bactericidal effect of TP and CET was proved. Chemotherapeutic effect of TP and CET ag...

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Veröffentlicht in:Japanese journal of antibiotics 1981/05/25, Vol.34(5), pp.647-650
Hauptverfasser: ISONO, MIDORI, AOKI, MAKOTO, KOBAYASHI, TOYOKO, MARUI, TOSHINORI, YAMADA, HISASHI, UMEMURA, ATSUSHI, WATANABE, KUNITOMO, UENO, KAZUE
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Sprache:jpn
Schlagworte:
Bacteroides fragilis
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Zusammenfassung:Synergistic effect of thiamphenicol (TP) and cephalothin (CET) on Bacteroides fragilis was proved in vitro. Especially its effect was much clear on B. fragilis which is possible to produce β-lactamase. Synergistic bactericidal effect of TP and CET was proved. Chemotherapeutic effect of TP and CET against experimental mixed infectious mouse due to E. coli (β-lactamase-) and B. fragilis (β-lactamase +) was proved.
ISSN:0368-2781
2186-5477
DOI:10.11553/antibiotics1968b.34.647